IN-VITRO STUDIES OF THE EFFECT OF ARSENIC ON THE BINDING OF METRONIDAZOLE AT THE BINDING SITES OF BOVINE SERUM ALBUMIN
نویسندگان
چکیده
The effect of arsenic on the binding metronidazole (an anti-amoebic agent) to bovine serum albumin (BSA) was studied by equilibrium dialysis (ED) method in order justify nature capability drug and BSA. There decrease concentration due addition arsenic. But free increased with increasing when only BSA present. result obtained no added 41% whereas this release 7% an from 0.5x10-5 10x10-5M. 36% 71% M to12x10-5M. This suggests that presence arsenic, shows a greater results decreased concentration. It could be suggested may form complex increases affinity its sites or metronidazole.
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ژورنال
عنوان ژورنال: Khulna University studies
سال: 2022
ISSN: ['1563-0897', '2789-2697']
DOI: https://doi.org/10.53808/kus.2005.6.1and2.0408-l